CHO-K1/ Mouse PD-L1 Stable Cell Line
Description
Programmed death-ligand 1 (PD-L1) also known as cluster of differentiation 274 (CD274) or B7 homolog 1 (B7-H1) is a protein that in humans is encoded by the CD274 gene. The formation of PD-1 receptor / PD-L1 or B7.1 receptor /PD-L1 ligand complex transmits an inhibitory signal which reduces the proliferation of these CD8+ T cells at the lymph nodes. After that PD-1 is also able to control the accumulation of foreign antigen specific T cells in the lymph nodes through apoptosis, which is further mediated by a downregulation of the Bcl-2 gene.
Internal Reference:
SA-CAS9-188
Website URL:
/shop/sa-cas9-188-cho-k1-mouse-pd-l1-stable-cell-line-33883
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