CD27 antibody [LT27] - 100 µg

Alternate_Names : CD27 , CD27 molecule , S152 , S152. LPFS2 , T14 , TNFRSF7 , Tp55 Applications : FACS Species_reactivity : Hu Clone : LT27 Storage_Buffer : PBS, 15mM Sodium azide. Concentration : 1 mg/mlsp Form : CD27 , CD27 molecule , S152 , S152. LPFS2 , T14 , TNFRSF7 , Tp55 References : The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and imm unoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapop totic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq, Jul 2008]