pHTS-Neo-ISRE

pHTS-Neo-ISRE is a cutting-edge luciferase reporter plasmid designed for studying interferon (IFN) signaling pathways in mammalian cells. This plasmid contains an ISRE (Interferon-Stimulated Response Element) linked to a luciferase reporter gene, allowing precise measurement of IFN-induced transcriptional activity. Ideal for high-throughput screening (HTS) applications, pHTS-Neo-ISRE enables researchers to investigate the molecular mechanisms of immune responses, specifically Type I and Type II interferon signaling. The system provides an easy-to-use, sensitive, and reliable assay to analyze interferon-stimulated gene expression and evaluate potential therapeutic agents that modulate the immune response. With the built-in neomycin resistance gene, pHTS-Neo-ISRE ensures stable selection in mammalian cells, making it a valuable tool for drug discovery and immune system research. - kit