Recombinant Human Beta Secretase 1 [BACE1], 50ug

The Recombinant Human Beta-Secretase 1 (BACE1) protein is a biologically active enzyme that catalyzes the β-site cleavage of amyloid precursor protein (APP), initiating the formation of amyloid-β (Aβ) peptides implicated in Alzheimer’s disease pathogenesis.

BACE1 is a type I transmembrane aspartic protease localized in the Golgi and endosomal membranes of neurons. It plays a pivotal role in the amyloidogenic processing pathway, making it a major therapeutic target for anti-Alzheimer’s drug discovery.

This recombinant BACE1 enzyme is expressed and purified to retain high enzymatic activity and native conformation, making it ideal for biochemical assays, drug screening, structural studies, and kinetic analyses.